Table of content
Editorials
Patching together a world view p761
Data sets encapsulating the behaviour of the Earth system are one of the greatest technological achievements of our age — and one of the most deserving of future investment.
doi:10.1038/450761a
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Africa's academies p762
Robust scientific institutions won't be built in a day.
doi:10.1038/450762a
Full Text | PDF (62K)
Shared genomes p762
Nature's publishers are expanding the licence for reuse of genome papers.
doi:10.1038/450762b
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News
Columbus begins voyage of discovery p766
Europe's space lab finally reaches the launch pad.
Geoff Brumfiel
doi:10.1038/450766a
Full Text | PDF (216K)
UN talks only one part of the negotiations needed on climate p767
Parallel discussions have important role to play.
Jeff Tollefson
doi:10.1038/450767a
Full Text | PDF (76K)
Solar power: California's latest gold rush p768
Green-energy companies are enjoying a boom in investment. But will they live up to expectation, asks Declan Butler.
Declan Butler
doi:10.1038/450768a
Full Text | PDF (298K)
Model predicts structure of crystals p771
Software solves long-standing chemical frustration.
Katharine Sanderson
doi:10.1038/450771a
Full Text | PDF (105K)
Sidelines p772
Scribbles on the margins of science.
doi:10.1038/450772a
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Saudi–Italian biomedical institute gets go-ahead p772
Hospital and cancer-research centre will form part of Red Sea development.
Alison Abbott
doi:10.1038/450772b
Full Text | PDF (179K)
Asia plans first cancer network p772
Regional initiative will coordinate data sharing and epidemiology.
David Cyranoski
doi:10.1038/450772c
Full Text | PDF (179K)
Fund boost for German science p773
Coalition government ploughs cash into research.
Quirin Schiermeier
doi:10.1038/450773a
Full Text | PDF (133K)
Safer way to make human stem-like cells revealed p775
doi:10.1038/450775a
Full Text | PDF (102K)
Risk analysis for Boston lab slammed as 'shoddy' p775
doi:10.1038/450775b
Full Text | PDF (102K)
AIDS worker's misconduct ban belatedly comes to light p775
doi:10.1038/450775c
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European satellite system is back on the launch pad p775
doi:10.1038/450775d
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Californian stem-cell directors to be investigated p775
doi:10.1038/450775e
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Endangered species cling on as rulings are overturned p775
doi:10.1038/450775f
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Business
Smart networking p777
Theoreticians have combined their expertise to form a network to help other scientists design materials or understand biological pathways. Katharine Sanderson reports.
Katharine Sanderson
doi:10.1038/450777a
Full Text | PDF (77K)
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News Features
Earth Monitoring: The planetary panopticon p778
Technology will soon allow the world to be mapped in near-real time and at high resolution. Declan Butler investigates the potential for operational monitoring of the planet.
doi:10.1038/450778a
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Earth Monitoring: Observing the ocean from within p780
doi:10.1038/450780a
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Earth Observation: Not enough eyes on the prize p782
The capacity of the United States to monitor Earth's vital signs is being stymied by tight budgets and poor coordination. Alexandra Witze reports.
doi:10.1038/450782a
Full Text | PDF (387K)
Earth Monitoring: The crucial measurement p785
doi:10.1038/450785a
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Correspondence
Thought: a different perspective p788
Marc D. Hauser
doi:10.1038/450788a
Full Text | PDF (76K)
Thought: book review has my ideas back to front p788
Steven Pinker
doi:10.1038/450788b
Full Text | PDF (76K)
Chance to learn and teach in the developing world p788
Tim Caro & Monique Borgerhoff Mulder
doi:10.1038/450788c
Full Text | PDF (76K)
Few women join ranks of Germany's academic élite p788
Laura Niven
doi:10.1038/450788d
Full Text | PDF (76K)
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Commentaries
Earth monitoring: Cinderella science p789
On-the-ground monitoring is unglamorous work, seldom rewarded by funding agencies or the science community. But we neglect it at our peril, warns Euan Nisbet.
doi:10.1038/450789a
Full Text | PDF (202K)
See also: Editor's summary
Earth monitoring: Vigilance is not enough p791
Global surveillance is key to tracking potential pandemic viruses such as H5N1. But we need to share samples more rapidly, increase testing in endemic areas and track more than one virus, argues Walter Boyce.
doi:10.1038/450791a
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Books and Arts
The ultimate Romantic adventure p793
Napoleon's invasion of the Middle East enhanced rather than diminished the world's intellectual heritage.
Andrew Robinson reviews Mirage: Napoleon's Scientists and the Unveiling of Egypt by Nina Burleigh
doi:10.1038/450793a
Full Text | PDF (191K)
Size matters, sometimes p794
Steven Murawski reviews Body Size: The Structure and Function of Aquatic Ecosystems
doi:10.1038/450794a
Full Text | PDF (130K)
The importance of nothing p795
Lawrence Rudnick reviews The Void by Frank Close
doi:10.1038/450795a
Full Text | PDF (159K)
Earth observation: A fresh perspective p795
Jennifer Meyer reviews Earth From Space by Andrew K. Johnston and Star Maps: History, Artistry, and Cartography by Nick Kanas and Spies in the Sky by Pat Norris
doi:10.1038/450795b
Full Text | PDF (159K)
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History of medicine: Ageing of plastic surgery p796
doi:10.1038/450796a
Full Text | PDF (106K)
Science in culture p796
Cartography and power have long gone hand in hand, as this pilgrimage plan illustrates.
Martin Kemp
doi:10.1038/450796b
Full Text | PDF (106K)
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Essay
Earth Monitoring: Whole Earth comes into focus p797
To understand how our planet uses energy, we must integrate genetic data from microbial studies with satellite views of our planet.
Stewart Brand
doi:10.1038/450797a
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News and Views
Diabetes: Missing links p799
Researchers have now probably pinpointed all the genes in the MHC genomic region that are risk factors in type 1 diabetes. As the MHC is unusually rich in genes involved in immunity, this is truly exciting.
Bart O. Roep
doi:10.1038/450799a
Full Text | PDF (355K)
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Condensed-matter physics: Shear madness p800
Cooled to temperatures just above absolute zero, solid helium starts to behave very oddly. But its 'supersolid' behaviour might just be the result of imperfections that change the bulk properties of the crystal.
Alan T. Dorsey & David A. Huse
doi:10.1038/450800a
Full Text | PDF (293K)
Relativity: Still special p801
Is special relativity a clapped-out classical theory, to be replaced by a shiny new quantum model as soon as possible? On the contrary, it would seem: the theory still has a youthful ability to surprise us.
Giovanni Amelino-Camelia
doi:10.1038/450801a
Full Text | PDF (156K)
Cancer: Immune pact with the enemy p803
Progress comes from the latest investigations into a long-standing question in immunology — the role of the immune system in maintaining small, potentially cancerous lesions in a state of dormancy.
Cornelis J. M. Melief
doi:10.1038/nature06363
Full Text | PDF (173K)
50 & 100 Years Ago p804
doi:10.1038/450804a
Full Text | PDF (104K)
Microbiology: Bilingual bacteria p805
Many bacteria use chemical signals to coordinate group behaviour. A signal that suppresses virulence has been identified in the bacterium that causes cholera, and could be a new therapeutic target.
Matthew R. Parsek
doi:10.1038/450805a
Full Text | PDF (176K)
See also: Editor's summary
Palaeoclimate: Slush find p807
A coupled model of palaeoclimate and carbon cycling turns up the heat on the idea that Earth once became a giant snowball. It supports instead a milder 'slushball Earth' history — but piquant questions remain.
Alan J. Kaufman
doi:10.1038/450807a
Full Text | PDF (158K)
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Oceanography: Siberian salt in the cellar p808
Richard Webb
doi:10.1038/450808a
Full Text | PDF (99K)
Obituary: Arthur Kornberg (1918–2007) p809
Passionate biochemist with a love for enzymes.
Tania A. Baker
doi:10.1038/450809a
Full Text | PDF (91K)
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News and Views Q&A
Sustainable technology: Green chemistry p810
Modern life depends on the petrochemical industry — most drugs, paints and plastics derive from oil. But current processes for making chemical products are not sustainable in terms of resources and environmental impact. Green chemistry aims to tackle this problem, and real progress is being made.
Martyn Poliakoff & Pete Licence
doi:10.1038/450810a
Full Text | PDF (165K)
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Brief Communications Arising
Effective global conservation strategies pE19
Ana S. L. Rodrigues
doi:10.1038/nature06374
First paragraph | Full Text | PDF (154K)
Grenyer et al. reply pE20
Richard Grenyer, C. David L. Orme, T. Jonathan Davies, Sarah F. Jackson, Richard G. Davies, Valerie A. Olson, Kate E. Jones, Kevin J. Gaston, Tim M. Blackburn, Gavin H. Thomas, Peter M. Bennett, Pamela C. Rasmussen, Tzung-Su Ding, John L. Gittleman & Ian P. F. Owens
doi:10.1038/nature06375
First paragraph | Full Text | PDF (154K)
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Articles
Snowball Earth prevention by dissolved organic carbon remineralization p813
W. Richard Peltier, Yonggang Liu & John W. Crowley
doi:10.1038/nature06354
Abstract | Full Text | PDF (2,239K) | Supplementary information
See also: Editor's summary | News and Views by Kaufman
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia p819
Wilhelm Roell, Thorsten Lewalter, Philipp Sasse, Yvonne N. Tallini, Bum-Rak Choi, Martin Breitbach, Robert Doran, Ulrich M. Becher, Seong-Min Hwang, Toktam Bostani, Julia von Maltzahn, Andreas Hofmann, Shaun Reining, Britta Eiberger, Bethann Gabris, Alexander Pfeifer, Armin Welz, Klaus Willecke, Guy Salama, Jan W. Schrickel, Michael I. Kotlikoff & Bernd K. Fleischmann
doi:10.1038/nature06321
Abstract | Full Text | PDF (1,349K) | Supplementary information
See also: Editor's summary
Bv8 regulates myeloid-cell-dependent tumour angiogenesis p825
Farbod Shojaei, Xiumin Wu, Cuiling Zhong, Lanlan Yu, Xiao-Huan Liang, Jenny Yao, Dominique Blanchard, Carlos Bais, Franklin V. Peale, Nicholas van Bruggen, Calvin Ho, Jed Ross, Martha Tan, Richard A. D. Carano, Y. Gloria Meng & Napoleone Ferrara
doi:10.1038/nature06348
Abstract | Full Text | PDF (579K) | Supplementary information
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The molecular architecture of cadherins in native epidermal desmosomes p832
Ashraf Al-Amoudi, Daniel Casta?o Díez, Matthew J. Betts & Achilleas S. Frangakis
doi:10.1038/nature05994
Abstract | Full Text | PDF (2,960K) | Supplementary information
Intrinsic motions along an enzymatic reaction trajectory p838
Katherine A. Henzler-Wildman, Vu Thai, Ming Lei, Maria Ott, Magnus Wolf-Watz, Tim Fenn, Ed Pozharski, Mark A. Wilson, Gregory A. Petsko, Martin Karplus, Christian G. Hübner & Dorothee Kern
doi:10.1038/nature06410
Abstract | Full Text | PDF (1,351K) | Supplementary information
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Letters
A stability limit for the atmospheres of giant extrasolar planets p845
Tommi T. Koskinen, Alan D. Aylward & Steve Miller
doi:10.1038/nature06378
First paragraph | Full Text | PDF (1,375K) | Supplementary information
See also: Editor's summary
Cryptomare magmatism 4.35 Gyr ago recorded in lunar meteorite Kalahari 009 p849
Kentaro Terada, Mahesh Anand, Anna K. Sokol, Addi Bischoff & Yuji Sano
doi:10.1038/nature06356
First paragraph | Full Text | PDF (861K)
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Low-temperature shear modulus changes in solid 4He and connection to supersolidity p853
James Day & John Beamish
doi:10.1038/nature06383
First paragraph | Full Text | PDF (1,103K) | Supplementary information
See also: News and Views by Dorsey & Huse
Controlling cavity reflectivity with a single quantum dot p857
Dirk Englund, Andrei Faraon, Ilya Fushman, Nick Stoltz, Pierre Petroff & Jelena Vu kovi
doi:10.1038/nature06234
First paragraph | Full Text | PDF (738K)
Linear and nonlinear optical spectroscopy of a strongly coupled microdisk–quantum dot system p862
Kartik Srinivasan & Oskar Painter
doi:10.1038/nature06274
First paragraph | Full Text | PDF (981K)
A crystallizing dense magma ocean at the base of the Earth's mantle p866
S. Labrosse, J. W. Hernlund & N. Coltice
doi:10.1038/nature06355
First paragraph | Full Text | PDF (498K) | Supplementary information
Host–parasite 'Red Queen' dynamics archived in pond sediment p870
Ellen Decaestecker, Sabrina Gaba, Joost A. M. Raeymaekers, Robby Stoks, Liesbeth Van Kerckhoven, Dieter Ebert & Luc De Meester
doi:10.1038/nature06291
First paragraph | Full Text | PDF (282K) | Supplementary information
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Methanotrophy below pH 1 by a new Verrucomicrobia species p874
Arjan Pol, Klaas Heijmans, Harry R. Harhangi, Dario Tedesco, Mike S. M. Jetten & Huub J. M. Op den Camp
doi:10.1038/nature06222
First paragraph | Full Text | PDF (280K) | Supplementary information
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Methane oxidation by an extremely acidophilic bacterium of the phylum Verrucomicrobia p879
Peter F. Dunfield, Anton Yuryev, Pavel Senin, Angela V. Smirnova, Matthew B. Stott, Shaobin Hou, Binh Ly, Jimmy H. Saw, Zhemin Zhou, Yan Ren, Jianmei Wang, Bruce W. Mountain, Michelle A. Crowe, Tina M. Weatherby, Paul L. E. Bodelier, Werner Liesack, Lu Feng, Lei Wang & Maqsudul Alam
doi:10.1038/nature06411
First paragraph | Full Text | PDF (411K) | Supplementary information
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The major Vibrio cholerae autoinducer and its role in virulence factor production p883
Douglas A. Higgins, Megan E. Pomianek, Christina M. Kraml, Ronald K. Taylor, Martin F. Semmelhack & Bonnie L. Bassler
doi:10.1038/nature06284
First paragraph | Full Text | PDF (328K) | Supplementary information
See also: Editor's summary| News and Views by Parsek
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A p887
Sergey Nejentsev, Joanna M. M. Howson, Neil M. Walker, Jeffrey Szeszko, Sarah F. Field, Helen E. Stevens, Pamela Reynolds, Matthew Hardy, Erna King, Jennifer Masters, John Hulme, Lisa M. Maier, Deborah Smyth, Rebecca Bailey, Jason D. Cooper, Gloria Ribas, R. Duncan Campbell, David G. Clayton, John A. Todd & The Wellcome Trust Case Control Consortium
doi:10.1038/nature06406
First paragraph | Full Text | PDF (588K) | Supplementary information
See also: Editor's summary | News and Views by Roep
Characterizing the cancer genome in lung adenocarcinoma p893
Barbara A. Weir, Michele S. Woo, Gad Getz, Sven Perner, Li Ding, Rameen Beroukhim, William M. Lin, Michael A. Province, Aldi Kraja, Laura A. Johnson, Kinjal Shah, Mitsuo Sato, Roman K. Thomas, Justine A. Barletta, Ingrid B. Borecki, Stephen Broderick, Andrew C. Chang, Derek Y. Chiang, Lucian R. Chirieac, Jeonghee Cho, Yoshitaka Fujii, Adi F. Gazdar, Thomas Giordano, Heidi Greulich, Megan Hanna, Bruce E. Johnson, Mark G. Kris, Alex Lash, Ling Lin, Neal Lindeman, Elaine R. Mardis, John D. McPherson, John D. Minna, Margaret B. Morgan, Mark Nadel, Mark B. Orringer, John R. Osborne, Brad Ozenberger, Alex H. Ramos, James Robinson, Jack A. Roth, Valerie Rusch, Hidefumi Sasaki, Frances Shepherd, Carrie Sougnez, Margaret R. Spitz, Ming-Sound Tsao, David Twomey, Roel G. W. Verhaak, George M. Weinstock, David A. Wheeler, Wendy Winckler, Akihiko Yoshizawa, Soyoung Yu, Maureen F. Zakowski, Qunyuan Zhang, David G. Beer, Ignacio I. Wistuba, Mark A. Watson, Levi A. Garraway, Marc Ladanyi, William D. Travis, William Pao, Mark A. Rubin, Stacey B. Gabriel, Richard A. Gibbs, Harold E. Varmus, Richard K. Wilson, Eric S. Lander & Matthew Meyerson
doi:10.1038/nature06358
First paragraph | Full Text | PDF (923K) | Supplementary information
See also: Editor's summary
Identification of protein pheromones that promote aggressive behaviour p899
Pablo Chamero, Tobias F. Marton, Darren W. Logan, Kelly Flanagan, Jason R. Cruz, Alan Saghatelian, Benjamin F. Cravatt & Lisa Stowers
doi:10.1038/nature05997
First paragraph | Full Text | PDF (458K) | Supplementary information
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Adaptive immunity maintains occult cancer in an equilibrium state p903
Catherine M. Koebel, William Vermi, Jeremy B. Swann, Nadeen Zerafa, Scott J. Rodig, Lloyd J. Old, Mark J. Smyth & Robert D. Schreiber
doi:10.1038/nature06309
First paragraph | Full Text | PDF (585K) | Supplementary information
See also: News and Views by Melief
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA p908
Jafar Sharif, Masahiro Muto, Shin-ichiro Takebayashi, Isao Suetake, Akihiro Iwamatsu, Takaho A. Endo, Jun Shinga, Yoko Mizutani-Koseki, Tetsuro Toyoda, Kunihiro Okamura, Shoji Tajima, Kohzoh Mitsuya, Masaki Okano & Haruhiko Koseki
doi:10.1038/nature06397
First paragraph | Full Text | PDF (798K) | Supplementary information
A hierarchy of timescales in protein dynamics is linked to enzyme catalysis p913
Katherine A. Henzler-Wildman, Ming Lei, Vu Thai, S. Jordan Kerns, Martin Karplus & Dorothee Kern
doi:10.1038/nature06407
First paragraph | Full Text | PDF (893K) | Supplementary information
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